Plasticity and Adaptation in Adult Binocular Vision

Zeynep Başgöze, Allyson P. Mackey, Emily A. Cooper

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Understanding the relationship between changes in sensory perception and functional/structural changes in the brain is a major endeavor in the field of systems neuroscience. Progress in this area holds the potential to reveal how the brain adapts to the demands of a complex and changing environment, as well as to assist with the development of therapeutic interventions to reverse the negative effects of abnormal experience. The cells and circuits that make up the mammalian visual system provide a unique scientific test-bed for studying brain plasticity, thanks to the rich literature on their basic organization and similarity across a range of species. In this minireview, we highlight recent advances in the study of plasticity in adult binocular vision, emphasizing the importance of considering changes that occur over different timescales. We discuss key new insights, significant open questions, and how this research is leading to a broader understanding of the ways that the adult brain maintains a robust ability for adaptation and change. In this minireview, Başgöze, Mackey and Cooper examine advances in understanding adult neuroplasticity, particularly plasticity in adult binocular vision, with an emphasis on changes that occur over different timescales.

Original languageEnglish (US)
Pages (from-to)R1406-R1413
JournalCurrent Biology
Issue number24
StatePublished - Dec 17 2018
Externally publishedYes

Bibliographical note

Funding Information:
The authors would like to thank Dennis Levi, Farran Briggs, Caroline Robertson, and Lanya Cai for helpful comments on earlier drafts of this manuscript. E.A.C. was supported by Oculus, Microsoft, and Intel. A.P.M. was supported by a Jacobs Foundation Research Fellowship.

Publisher Copyright:
© 2018 Elsevier Ltd

Copyright 2018 Elsevier B.V., All rights reserved.


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