Plasmonic materials for surface-enhanced sensing and spectroscopy

Amanda J. Haes, Christy L. Haynes, Adam D. McFarland, George C. Schatz, Richard P. Van Duyne, Shengli Zou

Research output: Contribution to journalReview articlepeer-review

602 Scopus citations


Localized surtace plasmon resonance (LSPR) excitation in silver and gold nanopartides produces strong extinction and scattering spectra that in recent years have been used for important sensing and spectroscopy applications. This article describes the fabrication, characterization, and computational electrodynamics of plasmonic materials that take advantage of this concept. Two applications of these plasmonic materials are presented: (1) the development of an ultrasensitive nanoscale optical biosensor based on LSPR wavelength-shift spectroscopy and (2) the use of plasmon-sampled and wavelength-scanned surface-enhanced Raman excitation spectroscopy (SERES) to provide new insight into the electromagnetic-field enhancement mechanism.

Original languageEnglish (US)
Pages (from-to)368-375
Number of pages8
JournalMRS Bulletin
Issue number5
StatePublished - May 2005

Bibliographical note

Funding Information:
The authors gratefully acknowledge support from the Air Force Office of Scientific Research MURI program (grant F49620-02-1-0381), the National Science Foundation (EEC-0118025, DMR-0076097, CHE-0414554), the Institute for Bioengineering and Nanoscience in Advanced Medicine at Northwestern University, and the National Institutes of Health (1 R21 DK066990-01A1).


  • Localized surface plasmon resonance spectroscopy
  • Nanosensing
  • Plasmonic materials
  • Surface-enhanced Raman spectroscopy


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