Plasma Arginine Vasopressin in Hyponatremic Patients with Heart Failure

Steven Goldsmith, Jay N Cohn, Gary S Francis, Allen Cowley, S. Smitz, J. J. Legros, J. L. Waucquez, P. A. Phillips, B. J. Rolls, J. G.G. Ledingham, Victoria L. Szatalowicz, Patricia E. Arnold, Cidio Chaimovitz, Daniel G. Bichet, Tomas Berl, Robert W. Schrier

Research output: Contribution to journalLetter

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Abstract

To the Editor: We offer the following comments in reference to the paper by Szatalowicz et al.1 in the July 30 issue, reporting detectable arginine vasopressin (AVP) levels in some hyponatremic patients with heart failure. Although 3.04±0.84 pg per milliliter was the mean value for AVP in the group with “detectable” levels, this number is somewhat misleading because of the presence of several very high values. Two thirds of the levels were actually below 2.0 pg per milliliter, and half of those were under 1.0 pg per milliliter. Thus, in most subjects, even in this group, AVP was nearly completely.

Original languageEnglish (US)
Pages (from-to)1470-1472
Number of pages3
JournalNew England Journal of Medicine
Volume305
Issue number24
DOIs
StatePublished - Dec 10 1981

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    Goldsmith, S., Cohn, J. N., Francis, G. S., Cowley, A., Smitz, S., Legros, J. J., Waucquez, J. L., Phillips, P. A., Rolls, B. J., Ledingham, J. G. G., Szatalowicz, V. L., Arnold, P. E., Chaimovitz, C., Bichet, D. G., Berl, T., & Schrier, R. W. (1981). Plasma Arginine Vasopressin in Hyponatremic Patients with Heart Failure. New England Journal of Medicine, 305(24), 1470-1472. https://doi.org/10.1056/NEJM198112103052412