Placental transfer of ganciclovir in a woman with acquired immunodeficiency syndrome and cytomegalovirus disease

Rebecca C. Brady; Mark R. Schleiss; David P. Witte; Tariq A. Siddiqi; Peter T. Frame

doi:10.1097/00006454-200208000-00023

Placental transfer of ganciclovir in a woman with acquired immunodeficiency syndrome and cytomegalovirus disease

Rebecca C. Brady, Mark R. Schleiss, David P. Witte, Tariq A. Siddiqi, Peter T. Frame

Pediatric Infectious Diseases

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

A pregnant woman with AIDS developed cytomegalovirus (CMV) retinitis and pneumonitis, requiring intravenous ganciclovir. At 34 weeks gestation the woman delivered a 1.4-kg girl. Examination of the placenta revealed transplacental passage of CMV. Low concentrations of ganciclovir were detected in the neonate's plasma. The neonate had mild anemia but no other signs of congenital CMV infection.

Original language	English (US)
Pages (from-to)	796-797
Number of pages	2
Journal	Pediatric Infectious Disease Journal
Volume	21
Issue number	8
DOIs	https://doi.org/10.1097/00006454-200208000-00023
State	Published - Aug 1 2002

Keywords

Acquired immunodeficiency syndrome
Congenital cytomegalovirus infection
Ganciclovir
Neonate

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/00006454-200208000-00023

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title = "Placental transfer of ganciclovir in a woman with acquired immunodeficiency syndrome and cytomegalovirus disease",

abstract = "A pregnant woman with AIDS developed cytomegalovirus (CMV) retinitis and pneumonitis, requiring intravenous ganciclovir. At 34 weeks gestation the woman delivered a 1.4-kg girl. Examination of the placenta revealed transplacental passage of CMV. Low concentrations of ganciclovir were detected in the neonate's plasma. The neonate had mild anemia but no other signs of congenital CMV infection.",

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AU - Brady, Rebecca C.

AU - Schleiss, Mark R.

AU - Witte, David P.

AU - Siddiqi, Tariq A.

AU - Frame, Peter T.

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AB - A pregnant woman with AIDS developed cytomegalovirus (CMV) retinitis and pneumonitis, requiring intravenous ganciclovir. At 34 weeks gestation the woman delivered a 1.4-kg girl. Examination of the placenta revealed transplacental passage of CMV. Low concentrations of ganciclovir were detected in the neonate's plasma. The neonate had mild anemia but no other signs of congenital CMV infection.

KW - Acquired immunodeficiency syndrome

KW - Congenital cytomegalovirus infection

KW - Ganciclovir

KW - Neonate

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Placental transfer of ganciclovir in a woman with acquired immunodeficiency syndrome and cytomegalovirus disease

Abstract

Keywords

UN SDGs

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