TY - JOUR
T1 - Physiological Pacing for the Prevention and Treatment of Heart Failure
T2 - a State-of-the-Art Review
AU - INFELD, MARGARET
AU - CYR, JAMIE A.
AU - SÁNCHEZ-QUINTANA, DAMIÁN
AU - MADIAS, CHRISTOPHER
AU - UDELSON, JAMES E.
AU - LUSTGARTEN, DANIEL L.
AU - MEYER, MARKUS
N1 - Publisher Copyright:
© 2024 Elsevier Inc.
PY - 2024/12
Y1 - 2024/12
N2 - Permanent pacing from the right ventricular apex can reduce quality of life and increase the risk of heart failure and death. This review summarizes the milestones in the evolution of pacemakers toward physiological pacing with biventricular pacing systems and lead implantation into the cardiac conduction system to synchronize cardiac contraction and relaxation. Both approaches aim to reproduce normal cardiac activation and help to prevent and treat heart failure. This review introduces the basic concepts and clinical evidence and discusses the practical uses of physiological pacing.
AB - Permanent pacing from the right ventricular apex can reduce quality of life and increase the risk of heart failure and death. This review summarizes the milestones in the evolution of pacemakers toward physiological pacing with biventricular pacing systems and lead implantation into the cardiac conduction system to synchronize cardiac contraction and relaxation. Both approaches aim to reproduce normal cardiac activation and help to prevent and treat heart failure. This review introduces the basic concepts and clinical evidence and discusses the practical uses of physiological pacing.
KW - Cardiac physiological pacing
KW - bundle branch block
KW - conduction system pacing
KW - heart failure
KW - pacing-induced cardiomyopathy
KW - resynchronization therapy
UR - http://www.scopus.com/inward/record.url?scp=85211253635&partnerID=8YFLogxK
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U2 - 10.1016/j.cardfail.2024.08.063
DO - 10.1016/j.cardfail.2024.08.063
M3 - Review article
C2 - 39481799
AN - SCOPUS:85211253635
SN - 1071-9164
VL - 30
SP - 1614
EP - 1628
JO - Journal of cardiac failure
JF - Journal of cardiac failure
IS - 12
ER -