Physical ventilatory weaning parameters in neonates and infants

A study was performed in neonates and infants under one year of age to establish criteria for and determine the efficacy of three bedside respiratory weaning parameters, namely, peak inspiratory negative pressure (PINP), inspiratory capacity (IC), and minute ventilation (VE). Bedside assessment of physical respiratory weaning parameters can offer useful information prior to extubation of infants requiring respiratory support. Of the 3 parameters measured, PINP and IC are more predictive. This has also been found true for adults. It appears that infants should exhibit PINPs of at least 30 torr and an IC of at least 100 ml/m² for successful extubation.