Photochemical micromachining of lysozyme crystals

Orlin D. Velev, Eric W. Kaler, Abraham M. Lenhoff

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Two complementary effects caused by the interaction of UV and visible light with lysozyme crystals infused with fluorescent surfactants allow for light-driven manipulation of protein arrays. The first is the photodegradation of lysozyme in the presence of pyrene, where the denatured protein subsequently dissolves and is etched off the crystal. The second is a phenomenon where the protein phase can be deposited, moved or dissolved by collimated light beams. Both effects can be used in the optical patterning and micromachining of protein crystals and other systems.

Original languageEnglish (US)
Pages (from-to)1345-1349
Number of pages5
JournalAdvanced Materials
Issue number16
StatePublished - Dec 1 1999


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