Phenomenological model of laser-tissue interaction with application to Benign Prostatic Hyperplasia (BPH) simulation

Xiangmin Zhou, Nan Zhang, Yunhe Shen, Dan Burke, Vamsi Konchada, Rob Sweet

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations


Laser-tissue interaction is a multi-physics phenomenon not yet mathematically describable and computationally predictable. It is a challenge to model the laser-tissue interaction for real time laser Benign Prostatic Hyperplasia (BPH) simulation which requires the laser-tissue interaction model to be computationally efficient and accurate. Under the consideration and enforcement of the thermodynamic first law and treating the laser-tissue interaction as a graybox, utilizing the sensitivity analysis of some key parameters that will affect the laser intensity on the tissue surface with respect to the tissue vaporization rate, a phenomenological model of laser-tissue interaction is developed. The developed laser-tissue interaction model has been implemented for a laser BPH simulator and achieves real time performance (more than 30 frames per second). The model agrees well with the available experimental data.

Original languageEnglish (US)
Title of host publicationMedicine Meets Virtual Reality 18
Subtitle of host publicationNextMed, MMVR18
PublisherIOS Press
Number of pages7
ISBN (Print)9781607507055
StatePublished - 2011

Publication series

NameStudies in Health Technology and Informatics
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365


  • Laser tissue interaction
  • Phenomenological Model


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