Phase II clinical trial of combination chemotherapy with dexamethasone for lymphoma in dogs

Chelsea B. Greenberg, Pedro A. Boria, Antonella Borgatti-Jeffreys, Rose E. Raskin, Michael D. Lucroy

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Dogs with histologically confirmed lymphoma were treated with a 14-week induction chemotherapy protocol that included dexamethasone. A phase II clinical trial was done using a standard two-stage design. Complete remission occurred in 21 (88%) dogs, with a median initial progression-free interval of 186 days. Toxicity was mild and self-limiting in the majority of dogs.

Original languageEnglish (US)
Pages (from-to)27-32
Number of pages6
JournalJournal of the American Animal Hospital Association
Volume43
Issue number1
DOIs
StatePublished - Jan 1 2007

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