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Pharmacokinetic enhancement of protease inhibitor therapy
Jennifer R. King
, Heather Wynn
, Richard Brundage
, Edward P. Acosta
Experimental and Clinical Pharmacology
Research output
:
Contribution to journal
›
Review article
›
peer-review
81
Scopus citations
Overview
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Keyphrases
Ritonavir
100%
Protease Inhibitor Therapy
100%
Pharmacokinetic Boosting
100%
Protease Inhibitors
66%
Proteinase Inhibitor
66%
Dual Protein
50%
Saquinavir
50%
Inhibitor Therapy
33%
Combination Regimen
33%
Lopinavir
33%
Cmin
33%
Plasma Concentration
16%
Clinical Data
16%
Healthy Volunteers
16%
Antiretroviral
16%
Metabolism
16%
Food Restriction
16%
Standard of Care
16%
Clinical Benefit
16%
Viral Replication
16%
EC50
16%
Absorption Mechanism
16%
IC50
16%
Pharmacokinetic Parameters
16%
Cytochrome P450 Enzymes
16%
Area under the Concentration-time Curve
16%
Treatment of HIV Infection
16%
Maximal Effect
16%
Pharmacokinetic Data
16%
Enzyme Inhibitors
16%
Combined Antiretroviral Therapy (cART)
16%
Antiviral Resistance
16%
Pharmacological Properties
16%
Resistance Increase
16%
Antiretroviral Resistance
16%
Metabolism Process
16%
Plasma Trough Concentration
16%
Pill Burden
16%
Pharmacology, Toxicology and Pharmaceutical Science
Ritonavir
100%
Proteinase Inhibitor
100%
Pharmacokinetics
100%
Protein Inhibitor
66%
Saquinavir
50%
Cmin
33%
Normal Human
16%
HIV
16%
Pharmacokinetic Parameter
16%
Cytochrome P450 Inhibitor
16%
Human Immunodeficiency Virus Infection
16%
Lopinavir
16%
Virus Resistance
16%
Lopinavir Plus Ritonavir
16%
IC50
16%
EC50
16%
Side Effect
16%