Pharmacokinetic assessment of efflux transport in sunitinib distribution to the Brain

Keyphrases

• Sunitinib 100%
• Pharmacokinetic Evaluation 100%
• Efflux Transport 100%
• Glioblastoma 50%
• Mdr1a 50%
• BCRP1 50%
• Multiforme 50%
• Clinical Trials 33%
• Blood-brain Barrier 33%
• P-glycoprotein (P-gp) 33%
• Genotype 33%
• Breast Cancer Resistance Protein 33%
• Elacridar 33%
• Brain Delivery 33%
• Dual Inhibitor 33%
• Transgenic 16%
• Targeted Delivery 16%
• Chemotherapy 16%
• Virus Strains 16%
• Tissue Distribution 16%
• Drug Transporters 16%
• Glioma Cells 16%
• Oral Dose 16%
• Transport Mechanism 16%
• Pharmacological Inhibitors 16%
• Wild Mice 16%
• Steady State 16%
• Xenograft Studies 16%
• Brain Distribution 16%
• Area under the Curve 16%
• Leukemia Virus 16%
• Brain Penetration 16%
• Brain-to-plasma Ratio 16%
• Distribution Coefficient 16%
• Linear Distribution 16%
• Genic 16%
• Distribution Kinetics 16%
• Transporter Inhibition 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Effusion 100%
• Sunitinib 100%
• Pharmacokinetics 100%
• Blastoma 50%
• Clinical Trial 33%
• P-Glycoprotein 33%
• Wild Type Mouse 33%
• ABCG2 33%
• Elacridar 33%
• Blood-Brain Barrier 33%
• Chemotherapy 16%
• Friend Murine Leukemia Virus 16%
• Virus Strain 16%
• Adjuvant 16%