Pharmacogenomics: Will the promise be fulfilled?

Russ B. Altman, Heyo K. Kroemer, Catherine A. McCarty, Mark J. Ratain, Dan Roden

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations

Abstract

Tools such as genome resequencing and genome-wide association studies have recently been used to uncover a number of variants that affect drug toxicity and efficacy, as well as potential drug targets. But how much closer are we to incorporating pharmacogenomics into routine clinical practice? Five experts discuss how far we have come, and highlight the technological, informatics, educational and practical obstacles that stand in the way of realizing genome-driven medicine.

Original languageEnglish (US)
Pages (from-to)69-73
Number of pages5
JournalNature Reviews Genetics
Volume12
Issue number1
DOIs
StatePublished - Jan 2011

Bibliographical note

Funding Information:
H.K.K.’s research is supported by the Federal Ministry of Education and Research (GANI_MED) and the Deutsche Forschungsgemeinschaft (SFB TR 19).

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