Abstract
The new aspect of our work is to reveal that Ph-like alterations are common among patients with Ph-ALL experiencing relapse after hematopoietic cell transplantation (HCT), despite acquisition of MRD-negative complete responses prior to transplant. This is also the central finding of our work. Therefore, the anticipated benefits of HCT appear diminished among this patient subset; such patients may be better served with efforts to further increase MRD depth prior to HCT, or alternative therapies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 406-408 |
| Number of pages | 3 |
| Journal | European Journal of Haematology |
| Volume | 109 |
| Issue number | 4 |
| DOIs | |
| State | Published - Oct 2022 |
Bibliographical note
Funding Information:This publication was made possible by an NIEHS‐funded predoctoral fellowship to S.T (T32HL007062).
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Chromosome Aberrations
- Hematopoietic Stem Cell Transplantation/adverse effects
- Humans
- Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis
- Recurrence
- Retrospective Studies
- Transplantation, Homologous
PubMed: MeSH publication types
- Letter
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