Personalized circadian timing of exercise

Ram B. Singh, Franz Halberg, Germaine Cornelissen, Jarmila Siegelova, Krasimira Hristova, Eri Toda, Toru Takahashi, Jan Fedacko, Kuniaki Otsuka

Research output: Chapter in Book/Report/Conference proceedingChapter


That exercise effects are circadian stage- dependent and that exercise at the wrong circadian stages can induce a Vascular Variability Disorder (VVD) has been documented earlier. Herein we show how statistically significant results can be obtained with a simple individualized design, that can be self-applied by everybody to optimize a desired effect by Chronobiologically-interpreted Ambulatory Blood Pressure (BP) and heart rate (HR) Monitoring C-ABPM). A 68-year old internist cardiologist monitored himself at half-hourly intervals, with interruptions, for 3- to7-day sessions, exercise timing being kept the same within a given session and changed from one session to another. Exercise training in the morning was associated with lowest BP and HR MESORs (Midline Estimating Statistic Of Rhythm, a rhythm-adjusted mean) as compared to exercise done at mid-day, late afternoon or in the evening. We review some of the literature, speculate about its meaning, yet do not stray beyond a single case in our conclusions for everybody: it seems possible and desirable to personalize exercise at a time of pertinence rather than convenience. One shoe or one timing does not fit all.

Original languageEnglish (US)
Title of host publicationCircadian Cardiology with Focus on both Prevention and Intervention
PublisherNova Science Publishers, Inc.
Number of pages16
ISBN (Electronic)9781634639996
ISBN (Print)9781634639569
StatePublished - Jan 1 2015

Bibliographical note

Publisher Copyright:
© 2015 Nova Science Publishers, Inc. All rights reserved.


  • Blood pressure
  • Circadian
  • Heart rate
  • Physical activity
  • Timing


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