Permeability of the normal round window membrane to haemophilus influenzae type b endotoxin

Lars Lundman, Steven K. Juhn, Dan Bagger-Sjöbäck, Catharina Svanborg

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Sensorineural hearing loss associated with otitis media may be due to passage of ototoxic substances such as bacterial toxins and antibiotics, from the middle ear into the inner ear. The round window membrane is the most likely route for such transport. The aim of this study was to analyze the extent of endotoxin passage through the normal round window membrane. The round window membranes of 19 chinchillas were exposed in vivo to Gelfoam

Original languageEnglish (US)
Pages (from-to)524-529
Number of pages6
JournalActa Oto-Laryngologica
Volume112
Issue number2
DOIs
StatePublished - 1992

Bibliographical note

Funding Information:
Supported by Grants from Tysta Skolan, the Swedish Medical Research Council (grant no. 00720) and the Sweden-America Foundation.

Keywords

  • Otitis media
  • Sensorineural hearing loss

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