Periprosthetic joint infection: The economic impact of methicillin-resistant infections

Javad Parvizi, Ian M. Pawasarat, Khalid A. Azzam, Ashish Joshi, Erik N. Hansen, Kevin J. Bozic

Research output: Contribution to journalArticlepeer-review

219 Scopus citations


The orthopedic community has begun to witness a worrisome rise in the incidence of periprosthetic joint infections (PJIs) caused by resistant organisms. Besides other challenges associated with treating these infections, it appears that these infections may pose a higher cost compared to infections caused by sensitive organisms. Significantly higher cost of care for treatment of infections due to methicillin-resistant organisms were seen at a mean of $107264 per case compared to $68053 for treating PJI caused by sensitive strains (P < 0001). More effective strategies for preventing the spread of infections caused by resistant organisms need to be implemented to ease the social and economic strains facing the orthopedic community due to resistant organisms.

Original languageEnglish (US)
Pages (from-to)103-107
Number of pages5
JournalJournal of Arthroplasty
Issue numberSUPPL. 6
StatePublished - Sep 2010
Externally publishedYes

Bibliographical note

Copyright 2012 Elsevier B.V., All rights reserved.


  • Cost
  • Infection
  • Methicillin resistance
  • Revision total joint arthroplasty


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