Perioperative management of hemophilia A during coronary artery bypass grafting with patent foramen ovale repair

Yash P. Vaidya, Theodore D. Hagmann, Sara Shumway

Research output: Contribution to journalArticlepeer-review

Abstract

Factor VIII deficiency, also known as hemophilia A, is the most common inherited bleeding disorder. Deficiency of Factor VIII results in dysfunction of platelet aggregation due to decreased activation of Factor X to Xa. We present the case of a 68-year-old male with mild hemophilia A (Factor VIII activity, 16%) who underwent a three-vessel coronary artery bypass graft and patent foramen ovale repair, with no increased bleeding utilizing a recombinant Factor VIII (kogenate) preoperative bolus and continuous infusion. His postoperative course was complicated by a sternal wound dehiscence requiring washout, sternal wire removal and omental flap coverage on postoperative Day 21. However, he required no postoperative blood transfusions.

Original languageEnglish (US)
Article numberrjae578
JournalJournal of Surgical Case Reports
Volume2024
Issue number9
DOIs
StatePublished - Sep 1 2024

Bibliographical note

Publisher Copyright:
© The Author(s) 2024.

Keywords

  • cardiopulmonary bypass
  • coronary artery bypass grafting
  • hemophilia

PubMed: MeSH publication types

  • Case Reports
  • Journal Article

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