Perinatal stroke causes abnormal trajectory and laterality in reaching during early infancy

Chao Ying Chen, Sara Tafone, Warren Lo, Jill C. Heathcock

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


The developmental progression of reaching and early signs of upper extremity neglect is common concern for infants at risk for hemiparesis and cerebral palsy. We investigated the emergence of reaching and laterality in infants at risk for hemiplegic cerebral palsy. Eight infants with perinatal stroke (PS) and thirteen infants with typical development (TD) were assessed bimonthly from 2 to 7 months of age for 10 visits per infant. Reaching number and hand-toy contact duration were measured. Infants with PS demonstrated a linear trajectory of reaching behaviors with asymmetrical upper extremity performance. Infants with TD demonstrated a linear and quadratic trajectory of reaching behaviors and symmetrical upper extremity performance over the same age range. These results suggest that infants with PS have delay reaching and early signs of neglect not currently accounted for in clinical practice.

Original languageEnglish (US)
Pages (from-to)301-308
Number of pages8
JournalResearch in Developmental Disabilities
StatePublished - Mar 1 2015

Bibliographical note

Publisher Copyright:
© 2014 Elsevier Ltd.


  • Infancy
  • Laterality
  • Motor control
  • Reaching
  • Stroke


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