Perils of diagnosis and detection of subungual squamous cell carcinoma

Priti P. Patel, Ian C. Hoppe, W. Robert Bell, W. Clark Lambert, Earl J. Fleegler

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Subungual squamous cell carcinoma often presents with atypical clinical manifestations, which can lead to delays in diagnosis. The presence of a tumor can be masked by the presence of infections or other misleading pathological conditions. The authors report on techniques for adequate biopsy and excision of such tumors. A case of subungual squamous cell carcinoma with invasion into the underlying bone is presented. Clinical histopathological evidence is reviewed along with human papillomavirus typing. Accurate diagnosis requires a high index of suspicion and appropriate tissue sampling.

Original languageEnglish (US)
Pages (from-to)S285-S287
JournalAnnals of Dermatology
Issue numberSUPPL. 3
StatePublished - Dec 2011


  • Nail biopsy
  • Nail deformity
  • Periungual squamous cell carcinoma
  • Subungual squamous cell carcinoma


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