Pericardiectomy is Associated with Improvement in Longitudinal Displacement of Left Ventricular Free Wall Due to Increased Counterclockwise Septal-to-Lateral Rotational Displacement

Kazuaki Negishi, Zoran B. Popović, Tomoko Negishi, Hirohiko Motoki, M Chadi Alraies, Srisakul Chirakarnjanakorn, Arun Dahiya, Allan L. Klein

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Background Pericardiectomy is an effective intervention for constrictive pericarditis. Speckle-tracking echocardiography can provide quantitative information not only about longitudinal strain (LS) but about longitudinal displacement (LD) and septal-to-lateral rotational displacement (SLRD). The aim of this study was to investigate whether pericardiectomy improves myocardial mechanics using speckle-tracking analysis. Methods Eighty-three patients with constrictive pericarditis who underwent echocardiography were retrospectively assessed (mean age, 58 ± 12 years; 72 men; 50 idiopathic, 20 postoperative, four viral, three radiation, and six others) and compared with 20 healthy volunteers. LD and SLRD were measured from the apical four-chamber view and global LS from three apical views. Results LD was less in the constrictive pericarditis group compared with control subjects (P <.001). Only lateral LS was significantly less than that of control subjects (P <.001), but septal LS was similar (P =.48). In pre- and post-pericardial surgery comparisons (n = 27), values of septal and lateral LD were almost identical (mean, 13.6 ± 4.7 vs 13.3 ± 5.4 mm; P =.70) before pericardiectomy, but septal LD decreased (mean, 9.3 ± 3.5 mm; P <.001) and lateral LD increased (mean, 16.8 ± 4.7 mm; P =.0106) after the surgery, even though the difference in LS between the septal and lateral walls decreased (from 5.6 ± 5.3% to 2.5 ± 4.2%, P =.008). Systolic whole-heart swinging motion significantly increased to a counterclockwise direction after surgery (mean SLRD, -0.8 ± 3.3° vs 2.1 ± 3.0°; P =.001). Although the change in SLRD after pericardiectomy was not different between patients with decreases and increases in New York Heart Association class, SLRD change was significantly greater in patients who received fewer diuretics after surgery (mean, 4.00 ± 0.91 vs 0.27 ± 1.47; P =.027). Conclusions After surgical removal of the pericardium, LD of the septal and lateral walls became significantly different, and counterclockwise SLRD increased, reflecting loss of pericardial support.

Original languageEnglish (US)
Pages (from-to)1204-1213
Number of pages10
JournalJournal of the American Society of Echocardiography
Volume28
Issue number10
DOIs
StatePublished - Oct 2015

Keywords

  • Constrictive pericarditis
  • Displacement
  • Longitudinal rotation
  • Pericardiectomy
  • Strain

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