Pericapsular nerve group (PENG) block for hip arthroscopy: a randomized, double-blinded, placebo-controlled trial

Peter E. Amato, John R. Coleman, Tomasz P. Dobrzanski, Donald A. Elmer, Frank W. Gwathmey, April E. Slee, Neil A. Hanson

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

INTRODUCTION: Arthroscopic hip surgery is associated with significant postoperative pain. Femoral nerve blocks have been shown to improve postoperative analgesia at the expense of quadriceps weakness. The pericapsular nerve group (PENG) block could be an alternative that may improve postoperative analgesia while preserving quadriceps strength. Our hypothesis was that a PENG block would provide superior postoperative analgesia compared with a sham block following arthroscopic hip surgery.

METHODS: Subjects presenting for arthroscopic hip surgery were randomized in a 1:1 ratio to either an ultrasound-guided unilateral, single-injection PENG block (PENG group) with 20 mL of 0.5% ropivacaine or a sham injection with 5 mL of 0.9% normal saline (Sham group) prior to receiving general anesthesia. The primary outcome of this study was worst pain score within 30 min of emergence from anesthesia. Secondary outcomes included opioid consumption, patient satisfaction with analgesia, opioid-related adverse events, and persistent opioid use at 1 week.

RESULTS: Sixty-eight subjects, 34 from the PENG group and 34 from the Sham group, completed the study per protocol. Analysis of the primary outcome demonstrated a mean difference in pain scores of -0.79 (95% CI -1.96 to 0.37; p=0.17) between the PENG and Sham groups immediately following surgery. No secondary outcomes showed statistically significant differences between groups.

DISCUSSION: This study demonstrates that a preoperative PENG block does not improve analgesia following arthroscopic hip surgery.

TRIAL REIGSTRATION NUMBER: NCT04508504.

Original languageEnglish (US)
Pages (from-to)728-732
Number of pages5
JournalRegional Anesthesia and Pain Medicine
Volume47
Issue number12
DOIs
StatePublished - Aug 23 2022

Bibliographical note

Funding Information:
This project was funded by the Department of Anesthesiology, University of Virginia, Charlottesville, Virginia, USA.

Publisher Copyright:
© 2022 BMJ Publishing Group. All rights reserved.

Keywords

  • Acute Pain
  • Ambulatory Care
  • Lower Extremity
  • Nerve Block
  • Ultrasonography

Fingerprint

Dive into the research topics of 'Pericapsular nerve group (PENG) block for hip arthroscopy: a randomized, double-blinded, placebo-controlled trial'. Together they form a unique fingerprint.

Cite this