Percutaneous Left Atrial Appendage Closure with the Watchman Device Long-Term Results Up to 5 Years

Jens Wiebe, Jennifer Franke, Katharina Lehn, Ilona Hofmann, Laura Vaskelyte, Stefan Bertog, Horst Sievert

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


Objectives The aim of this study was to evaluate long-term outcomes in patients with atrial fibrillation undergoing percutaneous left atrial appendage (LAA) closure with the Watchman device. Background Atrial fibrillation is one of the most common arrhythmias and is associated with a high risk for cardioembolic ischemic events, most notably stroke. Percutaneous LAA closure is an alternative to oral anticoagulation, because most thrombi originate from the LAA. Methods All consecutive patients with minimum CHADS2 or CHA2DS2-VASc scores of 1 who underwent LAA closure with the Watchman device between June 2006 and August 2010 were eligible. Follow-up examinations were performed after 45 days to 3 months, 6 months, and 1 year and thereafter annually. Afterward, alternating office visits and telephone follow-up were performed every 6 months. Results A total of 102 patients were included. The mean age was 71.6 ± 8.8 years, and 37.3% were women. The mean CHADS2 and CHA2DS2-VASc scores were 2.7 ± 1.3 and 4.3 ± 1.7, respectively. Procedural success was achieved in 96.1% of patients. During a mean follow-up period of 3.0 ± 1.6 years, the annual rates of transient ischemic attack, stroke, intracranial hemorrhage, and death were 0.7%, 0.7%, 1.1%, and 3.5%, respectively. Conclusions LAA closure with the Watchman device is safe and feasible for stroke protection in patients with atrial fibrillation. Low ischemic events rates demonstrate its effectiveness during long-term follow-up.

Original languageEnglish (US)
Pages (from-to)1915-1921
Number of pages7
JournalJACC: Cardiovascular Interventions
Issue number15
StatePublished - Dec 28 2015

Bibliographical note

Publisher Copyright:
© 2015 American College of Cardiology Foundation.


  • atrial fibrillation
  • left atrial appendage closure
  • stroke prevention


Dive into the research topics of 'Percutaneous Left Atrial Appendage Closure with the Watchman Device Long-Term Results Up to 5 Years'. Together they form a unique fingerprint.

Cite this