Perceived stress and change in cognitive function among adults 65 years and older

Neelum T. Aggarwal, Robert S. Wilson, Todd L. Beck, Kumar B. Rajan, Carlos F. Mendes De Leon, Denis A. Evans, Susan A. Everson-Rose

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Objective: Exposure to acute and chronic stress can affect learning and memory, but most evidence comes from animal studies or clinical observations. Almost no population-based studies have investigated the relation of stress to cognition or changes in cognition over time. We examined whether higher levels of perceived stress were associated with accelerated decline in cognitive function in older blacks and whites from a community-based population sample. Methods: Participants included 6207 black and white adults (65.7% black, 63.3% women) from the Chicago Health and Aging Project. Two to five in-home assessments were completed over an average of 6.8 years of follow-up and included sociodemographics, health behaviors, psychosocial measures, cognitive function tests, and health history. Perceived stress was measured by a six-item scale, and a composite measure of four tests of cognition was used to determine cognitive function at each assessment. Results: Mixed-effects regression models showed that increasing levels of perceived stress were related to lower initial cognitive scores (B =-0.0379, standard error = 0.0025, p <.001) and a faster rate of cognitive decline (stress × time interaction: B =-0.0015, standard error = 0.0004, p <.001). Results were similar after adjusting for demographic variables, smoking, systolic blood pressure, body mass index, chronic medical conditions, and psychosocial factors and did not vary by race, sex, age, or education. Conclusions: Increasing levels of stress are independently associated with accelerated declines in cognitive function in black and white adults 65 years and older.

Original languageEnglish (US)
Pages (from-to)80-85
Number of pages6
JournalPsychosomatic medicine
Volume76
Issue number1
DOIs
StatePublished - Jan 1 2014

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Keywords

  • aging
  • cognitive function
  • longitudinal
  • risk factors
  • stress

Cite this

Aggarwal, N. T., Wilson, R. S., Beck, T. L., Rajan, K. B., Mendes De Leon, C. F., Evans, D. A., & Everson-Rose, S. A. (2014). Perceived stress and change in cognitive function among adults 65 years and older. Psychosomatic medicine, 76(1), 80-85. https://doi.org/10.1097/PSY.0000000000000016

Perceived stress and change in cognitive function among adults 65 years and older. / Aggarwal, Neelum T.; Wilson, Robert S.; Beck, Todd L.; Rajan, Kumar B.; Mendes De Leon, Carlos F.; Evans, Denis A.; Everson-Rose, Susan A.

In: Psychosomatic medicine, Vol. 76, No. 1, 01.01.2014, p. 80-85.

Research output: Contribution to journalArticle

Aggarwal, NT, Wilson, RS, Beck, TL, Rajan, KB, Mendes De Leon, CF, Evans, DA & Everson-Rose, SA 2014, 'Perceived stress and change in cognitive function among adults 65 years and older', Psychosomatic medicine, vol. 76, no. 1, pp. 80-85. https://doi.org/10.1097/PSY.0000000000000016
Aggarwal NT, Wilson RS, Beck TL, Rajan KB, Mendes De Leon CF, Evans DA et al. Perceived stress and change in cognitive function among adults 65 years and older. Psychosomatic medicine. 2014 Jan 1;76(1):80-85. https://doi.org/10.1097/PSY.0000000000000016
Aggarwal, Neelum T. ; Wilson, Robert S. ; Beck, Todd L. ; Rajan, Kumar B. ; Mendes De Leon, Carlos F. ; Evans, Denis A. ; Everson-Rose, Susan A. / Perceived stress and change in cognitive function among adults 65 years and older. In: Psychosomatic medicine. 2014 ; Vol. 76, No. 1. pp. 80-85.
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