“Per protocol” practice patterns for Children's Oncology Group trials within the radiation oncology community

Kevin X. Liu; Lubna Hammoudeh; Daphne A. Haas-Kogan; Stephanie A. Terezakis

doi:10.1002/pbc.29673

“Per protocol” practice patterns for Children's Oncology Group trials within the radiation oncology community

Kevin X. Liu, Lubna Hammoudeh, Daphne A. Haas-Kogan, Stephanie A. Terezakis

Research output: Contribution to journal › Article › peer-review

Abstract

Little is known about the prevalence of pediatric radiation oncologists treating patients off study according to Children's Oncology Group (COG) trials before data are available regarding toxicity and efficacy of novel radiotherapy regimens. We conducted a 12-question survey of 358 pediatric radiation oncologists to characterize practice patterns regarding ongoing and completed COG protocols off study. With 130 responses (40.3%), the prevalence of providing treatment per protocol, but off study, before data are available in abstract or peer-reviewed form varied from 9.1% (for ACNS1422) to 88.1% (for AHOD1331). Future studies are needed to understand the effects of these practice patterns on outcomes.

Original language	English (US)
Article number	e29673
Journal	Pediatric Blood and Cancer
Volume	70
Issue number	8
DOIs	https://doi.org/10.1002/pbc.29673
State	Published - Aug 2023

Bibliographical note

Publisher Copyright:
© 2022 The Authors. Pediatric Blood & Cancer published by Wiley Periodicals LLC.

Keywords

Ewing sarcoma
Hodgkin lymphoma
ependymoma
medulloblastoma
neuroblastoma
rhabdomyosarcoma

PubMed: MeSH publication types

Journal Article

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/pbc.29673

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abstract = "Little is known about the prevalence of pediatric radiation oncologists treating patients off study according to Children's Oncology Group (COG) trials before data are available regarding toxicity and efficacy of novel radiotherapy regimens. We conducted a 12-question survey of 358 pediatric radiation oncologists to characterize practice patterns regarding ongoing and completed COG protocols off study. With 130 responses (40.3%), the prevalence of providing treatment per protocol, but off study, before data are available in abstract or peer-reviewed form varied from 9.1% (for ACNS1422) to 88.1% (for AHOD1331). Future studies are needed to understand the effects of these practice patterns on outcomes.",

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“Per protocol” practice patterns for Children's Oncology Group trials within the radiation oncology community

Abstract

Bibliographical note

Keywords

PubMed: MeSH publication types

UN SDGs

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