Peptide coupling using recyclable bicyclic benziodazolone

Daigo Uehara; Sota Adachi; Akira Tsubouchi; Yohei Okada; Viktor V. Zhdankin; Akira Yoshimura; Akio Saito

doi:10.1039/d3cc04431a

Peptide coupling using recyclable bicyclic benziodazolone

Daigo Uehara
, Sota Adachi
, Akira Tsubouchi
, Yohei Okada
, Viktor V. Zhdankin
, Akira Yoshimura
, Akio Saito

Chemistry & Biochemistry

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

We report a greener peptide coupling using bicyclic benziodazolone and triarylphosphine as coupling reagents. Bicyclic benziodazolone also works as a base and can be recovered as the corresponding iodine(i) compound after use, which can be converted to the original iodine(iii) reagent by electrolytic oxidation.

Original language	English (US)
Pages (from-to)	956-959
Number of pages	4
Journal	Chemical Communications
Volume	60
Issue number	8
DOIs	https://doi.org/10.1039/d3cc04431a
State	Published - Dec 18 2023

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© 2024 The Royal Society of Chemistry.

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10.1039/d3cc04431a

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abstract = "We report a greener peptide coupling using bicyclic benziodazolone and triarylphosphine as coupling reagents. Bicyclic benziodazolone also works as a base and can be recovered as the corresponding iodine(i) compound after use, which can be converted to the original iodine(iii) reagent by electrolytic oxidation.",

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AU - Uehara, Daigo

AU - Adachi, Sota

AU - Tsubouchi, Akira

AU - Okada, Yohei

AU - Zhdankin, Viktor V.

AU - Yoshimura, Akira

AU - Saito, Akio

PY - 2023/12/18

Y1 - 2023/12/18

N2 - We report a greener peptide coupling using bicyclic benziodazolone and triarylphosphine as coupling reagents. Bicyclic benziodazolone also works as a base and can be recovered as the corresponding iodine(i) compound after use, which can be converted to the original iodine(iii) reagent by electrolytic oxidation.

AB - We report a greener peptide coupling using bicyclic benziodazolone and triarylphosphine as coupling reagents. Bicyclic benziodazolone also works as a base and can be recovered as the corresponding iodine(i) compound after use, which can be converted to the original iodine(iii) reagent by electrolytic oxidation.

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UR - https://www.scopus.com/pages/publications/85180579786#tab=citedBy

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AN - SCOPUS:85180579786

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SP - 956

EP - 959

JO - Chemical Communications

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ER -

Peptide coupling using recyclable bicyclic benziodazolone

Abstract

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