Pediatric OCD in the era of RDoC

Sarah L. Garnaat, Christine A. Conelea, Nicole C.R. McLaughlin, Kristen Benito

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

The NIMH Research Domain Criteria (RDoC) initiative was established with the goal of developing an alternative research classification to further research efforts in mental health. While RDoC acknowledges that constructs should be considered within a developmental framework, developmental considerations have not yet been well integrated within the existing RDoC matrix. In this paper, we consider RDoC in relation to pediatric obsessive-compulsive disorder (OCD), a paradigmatic example of a neuropsychiatric disorder that often has onset in childhood but is also present across the lifespan. We discuss three RDoC subdomains with relevance to OCD as exemplars, providing for each construct a brief review of normative developmental changes, the state of construct-relevant research in pediatric OCD, and challenges and limitations related to developmental considerations within each subdomain. Finally, we conclude with a brief discussion of how RDoC may continue to evolve with regard to developmental considerations in order to further research in pediatric OCD.

Original languageEnglish (US)
Article number100385
JournalJournal of Obsessive-Compulsive and Related Disorders
Volume23
DOIs
StatePublished - Oct 2019

Bibliographical note

Funding Information:
Dr. Conelea is supported by the National Institutes of Health [K23MH103617] and Dr. McLaughlin is supported by the National Institutes of Health [K23MH100607]. The views expressed in this article are those of the authors and do not necessarily reflect the position or policy of the National Institutes of Mental Health

Funding Information:
Dr. Conelea is supported by the National Institutes of Health [ K23MH103617 ] and Dr. McLaughlin is supported by the National Institutes of Health [ K23MH100607 ]. The views expressed in this article are those of the authors and do not necessarily reflect the position or policy of the National Institutes of Mental Health

Publisher Copyright:
© 2019 Elsevier Ltd

Keywords

  • Obsessive-compulsive disorder
  • Research Domain Criteria (RDoC)

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