Patterns of treatment and associated short-term outcomes of unruptured intracranial aneurysms in children

Ganesh Asaithambi, Malik M. Adil, Kavisha M. Shah, Lori C. Jordan, Adnan I. Qureshi

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Background: The rates and outcomes of treatments for intracranial aneurysms have not been exclusively determined within the pediatric population. We determined the rates of endovascular and microsurgical treatments for unruptured intracranial aneurysms (UIA) and associated rates of favorable outcome in patients aged <18 years.

Methods: We analyzed data obtained as part of the Kids’ Inpatient Database between 2003 and 2009 with primary diagnosis of UIA. Patients undergoing endovascular treatment were compared to those undergoing microsurgical treatment. We determined rates of intracerebral hemorrhage, subarachnoid hemorrhage, neurological complications, and favorable outcome.

Results: There were 818 cases of UIA during the study period. A total of 111 patients (mean age 14 ± 6 years, 37.6 % female) underwent microsurgical treatment, and another 200 patients (mean age 13 ± 7 years, 42.5 % female) underwent endovascular treatment. A high rate of favorable outcome was observed in patients who received either treatment (microsurgical treatment 87.7 % versus endovascular treatment 91.6 %, p = 0.4). There was a trend towards a significantly shorter mean hospitalization stay among those who received endovascular treatment compared with microsurgical treatment (6 ± 12 versus 9 ± 11 days, p = 0.06). There was a significant trend towards higher utilization of endovascular treatment as opposed to microsurgical treatment from 2003 to 2009 (p = 0.02).

Conclusions: Although outcomes except for length of stay were comparable between endovascular treatment and microsurgical treatment patients, there was a trend towards higher utilization of endovascular treatment among children with UIAs from 2003 to 2009.

Original languageEnglish (US)
Pages (from-to)1697-1700
Number of pages4
JournalChild's Nervous System
Issue number10
StatePublished - 2014

Bibliographical note

Funding Information:
Disclosure The authors have not received any financial support for this work from any organization. A.I.Q. has received funding from the National Institutes of Health U01-NS062091-01A2 (medication provided by EKR Therapeutics), the American Heart Association Established Investigator Award 0840053 N, and the Minnesota Medical Foundation, Minneapolis, MN. The rest of the authors do not report any other conflicts of interest.


  • Endovascular treatment
  • Surgery
  • Unruptured intracranial aneurysm

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