Patient Psoas Muscle Mass as a Predictor of Complications and Survival After Radical Cystectomy

Hamed Ahmadi, James E. Montie, Alon Z. Weizer, Todd Morgan, Jeffrey S. Montgomery, Cheryl T. Lee

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

As a treatment for high-risk bladder cancer, radical cystectomy (RC) remains a highly morbid operation with complication rates of 40–60 % and mortality rates as high as 9 % in the first 90 days after surgery (Aziz et al., Eur Urol 66(1):156–163, 2014; Shabsigh et al., Eur Urol 55(1):164–174, 2009). Many patients suffer from a failure-to-thrive syndrome associated with anorexia, weight loss, dehydration, and immobility. In elderly patients, failure-to-thrive may result in loss of independence and a cascade of events that increases the risk of perioperative morbidity and mortality, ultimately resulting in impaired survival. Psoas muscle mass has been used to predict morbidity and mortality after major surgical procedures in vulnerable populations with substantial comorbidities. Increasingly, psoas muscle mass is also being used to predict outcomes after RC. If patients with a high risk of impaired survival are identified preoperatively, prehabilitative interventions can be integrated into their preparation for surgical treatment (Porserud et al., Clin Rehab 28(5):451–459, 2014; Friedman et al., Nutr Clin Pract: Off Publ Am Soc Parenter Enter Nutr 30(2):175–179, 2015). This chapter discusses the role of psoas muscle mass as a predictor of negative surgical outcomes after cystectomy.

Original languageEnglish (US)
Article number79
JournalCurrent Urology Reports
Volume16
Issue number11
DOIs
StatePublished - Nov 29 2015
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2015, Springer Science+Business Media New York.

Keywords

  • Complications
  • Morphomics
  • Psoas area
  • Radical cystectomy
  • Sarcopenia
  • Survival

Fingerprint

Dive into the research topics of 'Patient Psoas Muscle Mass as a Predictor of Complications and Survival After Radical Cystectomy'. Together they form a unique fingerprint.

Cite this