Pathophysiology of chronic graft-versus-host disease and therapeutic targets

Robert Zeiser, Bruce R. Blazar

Research output: Contribution to journalReview articlepeer-review

105 Scopus citations

Abstract

Chronic GVHD, an autoimmune disease that follows allogeneic hematopoietic-cell transplantation, is characterized by infections and debilitating tissue injury leading to irreversible fibrosis. Insights into the pathophysiology of the disease are providing new therapeutic targets.

Original languageEnglish (US)
Pages (from-to)2565-2579
Number of pages15
JournalNew England Journal of Medicine
Volume377
Issue number26
DOIs
StatePublished - Dec 28 2017

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