Pathophysiology and Clinical Presentation

Wouter Wieling, J. Gert van Dijk, Johannes J. van Lieshout, David G. Benditt

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
Original languageEnglish (US)
Title of host publicationThe Evaluation and Treatment of Syncope
Subtitle of host publicationA Handbook for Clinical Practice: Second Edition
PublisherJohn Wiley and Sons
Number of pages13
ISBN (Print)1405140305, 9781405140300
StatePublished - May 5 2009


  • Cerebrovascular autoregulation - permitting cerebral blood flow
  • Intravascular volume regulation - maintaining central blood volume
  • Loss of postural tone - inevitable consequence of loss of consciousness
  • Rapid short-term compensation
  • Tilt-table testing
  • Transient failure of protective mechanisms
  • Transient global cerebral hypoperfusion
  • Vasovagal syncope - common of neural reflex disorders
  • Widespread and excessive vasodilatation - critical role in decreasing arterial pressure

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