Pathology of the Lens

Amanda C. Maltry, J. Douglas Cameron

Research output: Chapter in Book/Report/Conference proceedingChapter


The crystalline lens is the second-most powerful refractive structure of the eye after the cornea. Cataract, opacity of the crystalline lens, is the most common cause of treatable vision loss. Cataract may develop within the anterior subcapsular, posterior subcapsular, cortical, and nuclear locations within the lens. Aberrant development of the lens can result in congenital lens opacities. Toxic exposure, metabolic disease, inflammatory conditions, and hereditary factors contribute to cataractogenesis. Defects in the lens zonular apparatus can result in lens subluxation or dislocation. Cataract surgery is the only therapeutic option to improve visually significant lens opacity.

Original languageEnglish (US)
Title of host publicationAlbert and Jakobiec's Principles and Practice of Ophthalmology
Subtitle of host publicationFourth Edition
PublisherSpringer International Publishing
Number of pages48
ISBN (Electronic)9783030426347
ISBN (Print)9783030426330
StatePublished - Jan 1 2022

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2022.


  • Accommodation
  • Anterior subcapsular cataract
  • Cataractogenesis
  • Cortical cataract
  • Crystalline lens
  • Lens capsule
  • Lens dislocation
  • Lens embryogenesis
  • Lens fibers
  • Nuclear cataract
  • Posterior subcapsular cataract
  • Pseudoexfoliation
  • Zonules


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