Pathology of the Lens

Amanda C. Maltry; J. Douglas Cameron

doi:10.1007/978-3-030-42634-7_137

Pathology of the Lens

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Abstract

The crystalline lens is the second-most powerful refractive structure of the eye after the cornea. Cataract, opacity of the crystalline lens, is the most common cause of treatable vision loss. Cataract may develop within the anterior subcapsular, posterior subcapsular, cortical, and nuclear locations within the lens. Aberrant development of the lens can result in congenital lens opacities. Toxic exposure, metabolic disease, inflammatory conditions, and hereditary factors contribute to cataractogenesis. Defects in the lens zonular apparatus can result in lens subluxation or dislocation. Cataract surgery is the only therapeutic option to improve visually significant lens opacity.

Original language	English (US)
Title of host publication	Albert and Jakobiec's Principles and Practice of Ophthalmology
Subtitle of host publication	Fourth Edition
Publisher	Springer International Publishing
Pages	6083-6130
Number of pages	48
ISBN (Electronic)	9783030426347
ISBN (Print)	9783030426330
DOIs	https://doi.org/10.1007/978-3-030-42634-7_137
State	Published - Jan 1 2022

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Publisher Copyright:
© Springer Nature Switzerland AG 2022.

Keywords

Accommodation
Anterior subcapsular cataract
Cataractogenesis
Cortical cataract
Crystalline lens
Lens capsule
Lens dislocation
Lens embryogenesis
Lens fibers
Nuclear cataract
Posterior subcapsular cataract
Pseudoexfoliation
Zonules

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10.1007/978-3-030-42634-7_137

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N2 - The crystalline lens is the second-most powerful refractive structure of the eye after the cornea. Cataract, opacity of the crystalline lens, is the most common cause of treatable vision loss. Cataract may develop within the anterior subcapsular, posterior subcapsular, cortical, and nuclear locations within the lens. Aberrant development of the lens can result in congenital lens opacities. Toxic exposure, metabolic disease, inflammatory conditions, and hereditary factors contribute to cataractogenesis. Defects in the lens zonular apparatus can result in lens subluxation or dislocation. Cataract surgery is the only therapeutic option to improve visually significant lens opacity.

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KW - Cataractogenesis

KW - Cortical cataract

KW - Crystalline lens

KW - Lens capsule

KW - Lens dislocation

KW - Lens embryogenesis

KW - Lens fibers

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KW - Posterior subcapsular cataract

KW - Pseudoexfoliation

KW - Zonules

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Pathology of the Lens

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