TY - JOUR
T1 - Pathogenesis of cachexia in cancer. A review and a hypothesis
AU - Theologides, Athanasios
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1972/2
Y1 - 1972/2
N2 - The clinical features of cachexia characterized by anorexia, marked asthenia, significant loss of body fat, protein and other components, anemia, water and electrolyte abnormalities and increased basal metabolic rate and energy expenditure despite the reduced dietary intake are just the most obvious manifestations of a profound systemic derangement of the host metabolism. A hypothesis to explain the pathogenesis of cancer cachexia is proposed.
AB - The clinical features of cachexia characterized by anorexia, marked asthenia, significant loss of body fat, protein and other components, anemia, water and electrolyte abnormalities and increased basal metabolic rate and energy expenditure despite the reduced dietary intake are just the most obvious manifestations of a profound systemic derangement of the host metabolism. A hypothesis to explain the pathogenesis of cancer cachexia is proposed.
UR - http://www.scopus.com/inward/record.url?scp=0015294312&partnerID=8YFLogxK
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U2 - 10.1002/1097-0142(197202)29:2<484::AID-CNCR2820290238>3.0.CO;2-E
DO - 10.1002/1097-0142(197202)29:2<484::AID-CNCR2820290238>3.0.CO;2-E
M3 - Article
C2 - 4552136
AN - SCOPUS:0015294312
VL - 29
SP - 484
EP - 488
JO - Cancer
JF - Cancer
SN - 0008-543X
IS - 2
ER -
