Abstract
Background: We studied the effect of partial aortic occlusion on cerebral perfusion and cardiac performance using the intra-aortic NeuroFlo™ catheter. Methods: Adult pigs were instrumented to determine cardiac parameters; unique isotope-labeled microspheres were used to determine cerebral blood flow (CBF) before, during and after sequential partial aortic occlusion. Results: Six pigs were studied; there was no relevant change in cardiac output, and the desired pressure drop of 10-15 mm Hg across the balloons was achieved. CBF increased significantly with inflation of the suprarenal balloon and remained elevated 90 min after deflation. Conclusions:Partial aortic occlusion with the NeuroFlo catheter significantly increased cerebral perfusion without adversely affecting cardiac performance.
Original language | English (US) |
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Pages (from-to) | 406-410 |
Number of pages | 5 |
Journal | Cerebrovascular Diseases |
Volume | 28 |
Issue number | 4 |
DOIs | |
State | Published - Sep 2009 |
Keywords
- Cerebral blood flow
- Cerebral perfusion augmentation
- Partial aortic occlusion