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PARP inhibition — not all gene mutations are created equal
Jun Luo,
Emmanuel S. Antonarakis
Research output
:
Contribution to journal
›
Article
›
peer-review
17
Scopus citations
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Keyphrases
BRCA1, BRCA2
100%
CDK12
100%
Gene mutation
100%
Homologous Recombination Deficiency
100%
Metastatic Castration-resistant Prostate Cancer (mCRPC)
100%
PARP Inhibitor (PARPi)
100%
Poly (ADP-ribose) Polymerase Inhibition
100%
Rucaparib
100%
Medicine and Dentistry
BRCA1
100%
BRCA2
100%
Castration Resistant Prostate Cancer
100%
Gene Mutation
100%
Homologous Recombination
100%
PARP Inhibitor
100%
Poly ADP Ribose Polymerase
100%
Rucaparib
100%
Pharmacology, Toxicology and Pharmaceutical Science
Castration Resistant Prostate Cancer
100%
Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase
100%
Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase Inhibitor
100%
Rucaparib
100%