Paramagnetic relaxation enhancement for protein-observed ¹⁹F NMR as an enabling approach for efficient fragment screening

Keyphrases

• 19F NMR 100%
• Fragment Screening 100%
• Paramagnetic Relaxation Enhancement 100%
• Enabling Approach 100%
• Ligand Discovery 33%
• Low Affinity 33%
• Longitudinal Relaxation 33%
• Relaxation Time 33%
• Emerging Tools 33%
• NMR Experiments 33%
• Chelates 33%
• Line Broadening 33%
• High-affinity Ligands 33%
• Time Lead 33%
• Ni(II) 33%
• Fragment-based Drug Discovery 33%
• Efficient Screening 33%

Biochemistry, Genetics and Molecular Biology

• Line Broadening 100%

Material Science

• Nuclear Magnetic Resonance 100%