Parallel synthesis of 9-aminoacridines and their evaluation against chloroquine-resistant Plasmodium falciparum

Keyphrases

• 9-Aminoacridine 100%
• Parallel Synthesis 100%
• Chloroquine-resistant Plasmodium Falciparum 100%
• 9-chloroacridine 100%
• Synthetic Strategies 50%
• Commercially Available 50%
• Disubstituted 50%
• Degradation Products 50%
• IC50 Value 50%
• Side Chain 50%
• Impurities 50%
• Two-strain 50%
• Plasmodium Falciparum 50%
• Acridone 50%
• Synthetic Intermediate 50%
• Diamine 50%
• Triflate 50%
• Aromatic Heterocyclic 50%
• Quinacrine 50%
• Substitution Pattern 50%
• Antimalarial Drugs 50%
• Drug-resistant Parasites 50%
• Salicylic Acid Derivatives 50%
• Incomplete Removal 50%

Chemistry

• 9-Aminoacridine 100%
• Parallel Synthesis 100%
• Chloroquine 100%
• Acridone 50%
• IC50 50%
• Heterocyclic Compound 50%
• Antimalarial Agent 50%
• Degradation Product 50%
• Salicylic Acid 50%
• Triflate 50%
• Quinacrine 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Chloroquine 100%
• Plasmodium falciparum 100%
• Aminoacridine 100%
• Antimalarial Agent 50%
• Salicylic Acid Derivative 50%
• Acridone Derivative 50%
• IC50 50%
• Mepacrine 50%