Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of babesiosis

Pankaj Gupta, Randolph W. Hurley, Peter H. Helseth, Jesse L. Goodman, Dale E Hammerschmidt

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


We present a case of hemophagocytosis during infection with the intraërythrocytic protozoan Babesia microti in a 47‐year‐old splenectomized renal allograft recipient. After therapy with clindamycin and quinine a relapse responded to atovaquone; durable remission was not achieved until trimethoprim/sulfa was added. We postulate the severity of our patient's syndrome was due to splenectomy and chronic immunosuppression. Babesiosis should be considered when immunocompromised patients develop pancytopenia.

Original languageEnglish (US)
Pages (from-to)60-62
Number of pages3
JournalAmerican Journal of Hematology
Issue number1
StatePublished - Sep 1995


  • Babesia
  • atovaquone
  • hemophagocytic syndrome
  • pancytopenia
  • renal transplant
  • splenectomy
  • trimethoprim/sulfamethoxazole


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