Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of babesiosis

Pankaj Gupta, Randolph W. Hurley, Peter H. Helseth, Jesse L. Goodman, Dale E Hammerschmidt

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

We present a case of hemophagocytosis during infection with the intraërythrocytic protozoan Babesia microti in a 47‐year‐old splenectomized renal allograft recipient. After therapy with clindamycin and quinine a relapse responded to atovaquone; durable remission was not achieved until trimethoprim/sulfa was added. We postulate the severity of our patient's syndrome was due to splenectomy and chronic immunosuppression. Babesiosis should be considered when immunocompromised patients develop pancytopenia.

Original languageEnglish (US)
Pages (from-to)60-62
Number of pages3
JournalAmerican Journal of Hematology
Volume50
Issue number1
DOIs
StatePublished - Sep 1995

Keywords

  • Babesia
  • atovaquone
  • hemophagocytic syndrome
  • pancytopenia
  • renal transplant
  • splenectomy
  • trimethoprim/sulfamethoxazole

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