Abstract
Successful pancreas transplantation continues to be the only treatment for insulin-dependent diabetes that durably restores euglycemia and metabolic control. The return of euglycemia and freedom from constant monitoring and multiple daily insulin injections or wearing a pump/monitor can significantly improve quality of life, stop the progression of diabetic complications, and in some cases is a life-saving procedure. Failure of a pancreas transplant reexposes the patient to their chronic disease state and its associated problems of dysglycemia, which can be physically and emotionally devastating. Since pancreas retransplantation is infrequently performed, few transplant centers or surgeons have substantive experience with the procedure which is currently now offered at decreasing number of centers. This chapter outlines the history and outcomes of pancreas retransplantation, key concerns in the evaluation of the retransplant candidate, surgical considerations, and an overview of the nuances of the different types and risks of pancreas retransplantation.
| Original language | English (US) |
|---|---|
| Title of host publication | Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas |
| Subtitle of host publication | Volume 1 |
| Publisher | Elsevier |
| Pages | 339-346 |
| Number of pages | 8 |
| ISBN (Electronic) | 9780128148334 |
| ISBN (Print) | 9780128148341 |
| DOIs | |
| State | Published - Jan 1 2019 |
Bibliographical note
Publisher Copyright:© 2020 Elsevier Inc. All rights reserved.
Keywords
- Outcome
- Pancreas
- Patient selection
- Retransplant
- Surgical technique
