Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Keyphrases

• Whole Genome 100%
• Pan-cancer Analysis 100%
• Retrotransposition 100%
• LINE-1 Retrotransposition 100%
• Cancer Genome 66%
• Head-and-neck Cancer 33%
• Oncogenesis 33%
• Colorectal Cancer 33%
• Tumor Suppressor Gene 33%
• All Cancer 33%
• Oncogene 33%
• Genome Project 33%
• Retrotransposon 33%
• Duplication 33%
• Long Interspersed nuclear element-1 (LINE-1) 33%
• Human Tumors 33%
• Cancer Subtypes 33%
• Esophageal Adenocarcinoma 33%
• Event Type 33%
• Somatic Integration 33%
• High-level Amplifications 33%
• L1 Retrotransposition 33%
• Complex Translocation 33%
• Hereafter 33%
• Somatic Structural Variation 33%

Biochemistry, Genetics and Molecular Biology

• Retrotransposon 100%
• Oncogene 100%
• Tumor Suppressor Gene 100%
• Autosome 100%
• Long Interspersed Nuclear Element 100%
• Carcinogenesis 100%

Medicine and Dentistry

• Malignant Neoplasm 100%
• Somatics 66%
• Head and Neck Cancer 16%
• Neoplasm 16%
• Retroposon 16%
• Carcinogenesis 16%
• Tumor Suppressor Gene 16%
• Oncogene 16%
• Colorectal Carcinoma 16%
• Esophageal Adenocarcinoma 16%
• Autosome 16%