Oxidation of benzyl alcohols with difluoro(aryl)-λ3-bromane: formation of benzyl fluoromethyl ethers via oxidative rearrangement

Masahito Ochiai, Akira Yoshimura, Kazunori Miyamoto

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Oxidative rearrangement of benzyl alcohols with difluoro(p-trifluoromethylphenyl)-λ3-bromane (5 × 10-2 M) in chloroform at room temperature afforded aryl fluoromethyl ethers selectively in good yields, probably via 1,2-shift of aryl groups from benzylic carbon to oxygen atoms.

Original languageEnglish (US)
Pages (from-to)4792-4795
Number of pages4
JournalTetrahedron Letters
Issue number33
StatePublished - Aug 18 2009
Externally publishedYes

Bibliographical note

Funding Information:
We gratefully acknowledge the Ministry of Education, Culture, Sports, Science, and Technology of Japan for financial support in the form of a grant.


  • Alcohol
  • Bromine
  • Ether
  • Hypervalent
  • Oxidation
  • Rearrangement


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