Oxalosis. An unusual cause of myelophthisis in childhood

Robert W McKenna, L. P. Dehner

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


In a girl of 5 with renal failure and oliguria due to hyperoxaluria myelophthisis developed as a result of extensive bone marrow replacement with calcium oxalate crystals and an accompanying fibrous proliferation. The histopathology associated with this metabolic disorder was demonstrated in posterior iliac crest bone marrow trephine biopsies, renal biopsies, and nephrectomy specimens. Crystals were demonstrated in biopsy specimens of transplanted kidneys within 6 wk following renal transplantation.

Original languageEnglish (US)
Pages (from-to)991-997
Number of pages7
JournalAmerican journal of clinical pathology
Issue number6
StatePublished - Jan 1 1976


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