Overview of Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) Support for the Management of Cardiogenic Shock

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations
131 Downloads (Pure)


Cardiogenic shock accounts for ~100,000 annual hospital admissions in the United States. Despite improvements in medical management strategies, in-hospital mortality remains unacceptably high. Multiple mechanical circulatory support devices have been developed with the aim to provide hemodynamic support and to improve outcomes in this population. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is the most advanced temporary life support system that is unique in that it provides immediate and complete hemodynamic support as well as concomitant gas exchange. In this review, we discuss the fundamental concepts and hemodynamic aspects of VA-ECMO support in patients with cardiogenic shock of various etiologies. In addition, we review the common indications, contraindications and complications associated with VA-ECMO use.

Original languageEnglish (US)
Article number686558
Pages (from-to)1-17
JournalFrontiers in Cardiovascular Medicine
StatePublished - 2021

Bibliographical note

Publisher Copyright:
Copyright © 2021 Tsangaris, Alexy, Kalra, Kosmopoulos, Elliott, Bartos and Yannopoulos.


  • cardiogenic shock
  • extracorporeal membrane oxygenation
  • mechanical circulatory support
  • VA-ECMO complications
  • VA-ECMO indications

Cite this