Outgrowing schwannomas arising from tympanic segments of the facial nerve

Quanan Zhang, Jose Jessurun, Patricia A. Schachern, Michael M. Paparella, Sherry Fulton

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12 Scopus citations


Purpose: Although there have been numerous reports of clinical cases of facial nerve schwannoma, histopathologic studies of its early stages of development are rare. The purpose of this study was to describe the incidence, origin, and pathology of small, asymptomatic schwannomas of the facial nerve. Materials and Methods: Fifteen hundred twenty-six ears from the human temporal bone collection of the Otitis Media Research Center Otopathology Laboratory at the University of Minnesota were studied under light microscopy. Results: Twelve bones with morphologic indications of type A Antoni tissue that mimics facial schwannoma in the tympanic cavity were selected. The 12 ears were from nine individuals with asymptomatic histories. The twelve schwannomas developed from perineurium at dehiscences in the facial canal near the oval window, forming defects in the epineurium by growth of Schwann cells downward and outward toward the stapes. No obvious compressions or lesions within fibers in the facial nerve were observed. Conclusion: Because these tumors grow slowly without hearing loss or facial nerve symptoms, they may be mistaken for granulation tissue during surgery for chronic otitis media.

Original languageEnglish (US)
Pages (from-to)311-315
Number of pages5
JournalAmerican Journal of Otolaryngology - Head and Neck Medicine and Surgery
Issue number5
StatePublished - Jan 1 1996

Bibliographical note

Funding Information:
From the Department of Otolatyngology, University of Minnesota Otitis Media Research Center, the Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, and the Minnesota Ear, Head, and Neck Clinic, Minneapolis, MN. Supported in part by NIH Grant POl-DC00133 from the National Institute on Deafness of Other Communicative Disorder and by the International Hearing Foundation. Address reprint requests to Patricia Schachern, BS, Dept of Otolaryngology, University of Minnesota, Rm 226 Lions Research Bldg, 2001 6th Street SE, Minneapolis, MN 55455. Copyright 0 1996 by W.B. Saunders Company 0196-0709/96/l 705-0006$5.00/O


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