Outcomes of Unilateral Cataracts in Infants and Toddlers 7 to 24 Months of Age: Toddler Aphakia and Pseudophakia Study (TAPS)

Toddler Aphakia and Pseudophakia Study Group (TAPS)

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12 Scopus citations

Abstract

Purpose: To evaluate outcomes of unilateral cataract surgery in children 7 to 24 months of age. Design: Retrospective case series at 10 Infant Aphakia Treatment Study (IATS) sites. Participants: The Toddler Aphakia and Pseudophakia Study is a registry of children treated by surgeons who participated in the IATS. Methods: Children underwent unilateral cataract surgery with or without intraocular lens (IOL) placement during the IATS enrollment years of 2004 and 2010. Main Outcome Measures: Intraoperative complications, adverse events (AEs), visual acuity, and strabismus. Results: Fifty-six children were included with a mean postoperative follow-up of 47.6 months. Median age at cataract surgery was 13.9 months (range, 7.2–22.9). Ninety-two percent received a primary IOL. Intraoperative complications occurred in 4 patients (7%). At 5 years of age, visual acuity of treated eyes was very good (≥20/40) in 11% and poor (≤20/200) in 44%. Adverse events were identified in 24%, with a 4% incidence of glaucoma suspect. An additional unplanned intraocular surgery occurred in 14% of children. Neither AEs nor intraocular reoperations were more common for children with surgery at 7 to 12 months of age than for those who underwent surgery at 13 to 24 months of age (AE rate, 21% vs. 25% [P = 0.60]; reoperation rate, 13% vs. 16% [P = 1.00]). Conclusions: Although most children underwent IOL implantation concurrent with unilateral cataract removal, the incidence of complications, reoperations, and glaucoma was low when surgery was performed between 7 and 24 months of age and compared favorably with same-site IATS data for infants undergoing surgery before 7 months of age. Our study showed that IOL implantation is relatively safe in children older than 6 months and younger than 2 years.

Original languageEnglish (US)
Pages (from-to)1189-1195
Number of pages7
JournalOphthalmology
Volume126
Issue number8
DOIs
StatePublished - Aug 2019

Bibliographical note

Funding Information:
Supported by the Mayo Clinic, Rochester, Minnesota (CCaTS grant UL1TR000135). The sponsor or funding organization had no role in the design or conduct of this research.

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