Outcomes of infants <28 days old treated with peritoneal dialysis for end-stage renal disease

Michelle N Rheault, Jurat Rajpal, Blanche M Chavers, Thomas E Nevins

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

This study evaluates the long-term outcomes of infants with end stage renal disease (ESRD) who required initiation of chronic peritoneal dialysis (PD) prior to 28 days of age. Infants with ESRD present both ethical and technical challenges for pediatric nephrologists and neonatologists. Recent advances in the medical management of ESRD in infants combined with improved infant transplantation outcomes make it more likely that such infants can survive to successful kidney transplantation. We reviewed all infants initiating PD for ESRD before 28 days of age at the University of Minnesota Amplatz Children's Hospital from 1995 to 2004 (n=23). Overall 1 - and 5-year patient survival was 52 and 48%, respectively. Twelve children received kidney transplants at a median age and weight of 1.12 years and 9.5 kg, respectively, with a 5-year graft survival rate of 83%. In summary, a majority of infants requiring renal replacement therapy with PD in the first month of life achieve long-term survival with a successful kidney transplant.

Original languageEnglish (US)
Pages (from-to)2035-2039
Number of pages5
JournalPediatric Nephrology
Volume24
Issue number10
DOIs
StatePublished - 2009

Keywords

  • Infant
  • Peritoneal dialysis
  • Renal replacement therapy
  • Transplantation

Fingerprint

Dive into the research topics of 'Outcomes of infants <28 days old treated with peritoneal dialysis for end-stage renal disease'. Together they form a unique fingerprint.

Cite this