Osteosarcoma of the anterior maxilla mimicking a periapical pathology: A case report

Mariana Domingos Pires, Jorge N.R. Martins, Gonçalo Seguro Dias, D. Doutel, Ronald Ordinola-Zapata

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1 Scopus citations


Osteosarcomas of the jaws (OSJ) are difficult to diagnose, rare malignant lesions, with uncharacteristic radiographic and clinical presentation. Early diagnosis and treatment are essential to improve long-term prognosis. The current report presents a rare case of a primary conventional osteoblastic osteosarcoma of the anterior maxilla in a 25-year-old female. She presented to a private dental clinic after developing pain, facial oedema and palpation tenderness of a mass associated with the upper right lateral incisor. The signs and symptoms mimicked very closely a regular radiolucent and symptomatic periapical pathology, and the definitive diagnosis was only possible through a combination of clinical, radiographic and histopathological findings. The patient was referred to an oncology facility, where she was submitted to radical excision surgery through a hemi-maxillectomy. Although other pathologies are uncommon, the differential diagnosis of lesions compatible with odontogenic periapical pathology should not be neglected.

Original languageEnglish (US)
Pages (from-to)656-663
Number of pages8
JournalAustralian Endodontic Journal
Issue number3
Early online dateFeb 18 2021
StatePublished - Dec 2021

Bibliographical note

Funding Information:
Nothing to declare.

Publisher Copyright:
© 2021 Australian Society of Endodontology Inc


  • diagnoses
  • endodontics
  • oral cancer
  • oral surgery
  • osteosarcoma tumour


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