Osteosarcoma of the anterior maxilla mimicking a periapical pathology: A case report

Mariana Domingos Pires, Jorge N.R. Martins, Gonçalo Seguro Dias, Delfim Doutel, Ronald Ordinola-Zapata

Research output: Contribution to journalArticlepeer-review


Osteosarcomas of the jaws (OSJ) are difficult to diagnose, rare malignant lesions, with uncharacteristic radiographic and clinical presentation. Early diagnosis and treatment are essential to improve long-term prognosis. The current report presents a rare case of a primary conventional osteoblastic osteosarcoma of the anterior maxilla in a 25-year-old female. She presented to a private dental clinic after developing pain, facial oedema and palpation tenderness of a mass associated with the upper right lateral incisor. The signs and symptoms mimicked very closely a regular radiolucent and symptomatic periapical pathology, and the definitive diagnosis was only possible through a combination of clinical, radiographic and histopathological findings. The patient was referred to an oncology facility, where she was submitted to radical excision surgery through a hemi-maxillectomy. Although other pathologies are uncommon, the differential diagnosis of lesions compatible with odontogenic periapical pathology should not be neglected.

Original languageEnglish (US)
JournalAustralian Endodontic Journal
Early online dateFeb 18 2021
StateE-pub ahead of print - Feb 18 2021

Bibliographical note

Publisher Copyright:
© 2021 Australian Society of Endodontology Inc


  • diagnoses
  • endodontics
  • oral cancer
  • oral surgery
  • osteosarcoma tumour

PubMed: MeSH publication types

  • Case Reports


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