Osteoporosis after stem cell transplantation

Brian L McClune, Navneet S. Majhail

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

With long-term survival for recipients of autologous and allogeneic hematopoietic cell transplantation (HCT) increasing, the recognition of late complications such as decreased bone mineral density leading to osteoporosis (OP) has also increased. With an incidence that is reported to affect as many 50 % of allo HCT recipients, studies continue to mount supporting the need and success in treatment of this HCT complication. In this review, we highlight the major pathological mechanisms behind the development of OP, its diagnosis, and the literature supporting consensus treatment recommendations while noting areas of uncertainty that need further research.

Original languageEnglish (US)
Pages (from-to)305-310
Number of pages6
JournalCurrent Osteoporosis Reports
Volume11
Issue number4
DOIs
StatePublished - Dec 1 2013

Fingerprint

Cell Transplantation
Stem Cell Transplantation
Osteoporosis
Bone Density
Uncertainty
Incidence
Therapeutics
Research

Keywords

  • Allogeneic stem cell transplant
  • Autologous stem cell transplant
  • Osteopenia
  • Osteoporosis
  • Review
  • Skeletal complications

Cite this

Osteoporosis after stem cell transplantation. / McClune, Brian L; Majhail, Navneet S.

In: Current Osteoporosis Reports, Vol. 11, No. 4, 01.12.2013, p. 305-310.

Research output: Contribution to journalArticle

McClune, Brian L ; Majhail, Navneet S. / Osteoporosis after stem cell transplantation. In: Current Osteoporosis Reports. 2013 ; Vol. 11, No. 4. pp. 305-310.
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