Ornithobacterium rhinotracheale infection in turkeys: Immunoprophylaxis studies

Stephanie J. Sprenger, David A. Halvorson, Daniel P. Shaw, K. V. Nagaraja

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Ornithobacterium rhinotracheale has been shown to cause serious clinical illness and is a significant concern to the turkey industry because of its potential economic impact. In this study, 6-wk-old turkeys were vaccinated intranasally with a live or subcutaneously with a killed O. rhinotracheale vaccine. At 14 or 21 wk of age, the birds were challenged intratracheally with live O. rhinotracheale. Airsacculitis and pneumonia occurred less frequently in vaccinated birds than in unvaccinated birds after challenge with O. rhinotracheale. Ornithobacterium rhinotracheale was recovered from unvaccinated, challenged birds but not from vaccinated, challenged or from unchallenged birds. Thus, turkeys inoculated with live or killed O. rhinotracheale vaccine were protected from pathologic changes.

Original languageEnglish (US)
Pages (from-to)549-555
Number of pages7
JournalAvian diseases
Issue number3
StatePublished - Jan 1 2000


  • Ornithobacterium rhinotracheale
  • Turkey
  • Vaccine


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