Origin of the different pH activity profile in two homologous ketosteroid isomerases

Keyphrases

• Ketosteroid Isomerase 100%
• Activity Profile 100%
• Catalytic Base 100%
• Catalytic Activity 66%
• Acidic pH 66%
• Indole Ring 66%
• Hydrogen Bond (H-bond) 66%
• Protein Engineering 33%
• Tryptophan 33%
• Kinetic Parameters 33%
• Novel Enzymes 33%
• CRISTAL 33%
• Molecular Evolution 33%
• Carboxyl 33%
• Catalytic Function 33%
• Pseudomonas Putida 33%
• Low pH 33%
• Kcat 33%
• Km Value 33%
• Comamonas Testosteroni 33%
• Protonation 33%
• PH Level 33%
• Substrate Affinity 33%
• Biotype B 33%
• 3-ketosteroids 33%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• Isomerase 100%
• Hydrogen Bond 66%
• Enzymatic Activity 66%
• Kinetic Parameter 33%
• Crystal Structure 33%
• Catalytic Efficiency 33%
• Pseudomonas putida 33%
• Comamonas testosteroni 33%
• Biotype 33%
• Molecular Evolution 33%
• Protonation 33%
• Protein Engineering 33%
• Tryptophan 33%

Chemistry

• Base 100%
• Hydrogen Bonding 66%
• Indole 66%
• Catalyst Activity 66%
• Pharmacokinetics 33%
• Dioxygen 33%
• Crystal Structure 33%
• Dissociation Exponent 33%
• Kcat/Km 33%
• Tryptophan 33%
• protonation 33%