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Organic peroxides inhibit neutrophil leukotriene B
4
biosynthesis
I. J. Okazaki
, L. M. Newman
, D. W. Allen
Medicine - Veteran's Administration Medical Center
Medicine - Hematology, Oncology, Transplant
Research output
:
Contribution to journal
›
Article
›
peer-review
1
Scopus citations
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4
biosynthesis'. Together they form a unique fingerprint.
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Keyphrases
5-lipoxygenase (5-LOX)
60%
50% Inhibitory Concentration
20%
Adhesion
20%
Arachidonic Acid
20%
Autacoids
20%
Catalase
40%
Chemokinesis
20%
Chemotaxis
20%
Damaged Tissue
20%
Dose Effect
20%
Erythrocyte Ghosts
20%
Generating System
20%
Ghosts
20%
Hydrogen Peroxide
40%
Hydroperoxides
20%
Inflammation
60%
Leukotriene A4 Hydrolase
20%
Leukotriene B4 (LTB4)
100%
Lipid Peroxides
20%
Lipid Solubility
20%
Membrane Peroxidation
20%
Neutrophil Infiltration
40%
Neutrophils
100%
Organic Peroxides
100%
Oxidative Damage
20%
Oxidized Lipids
20%
Peracetic Acid
20%
Peroxidative
20%
Polymorphonuclear Neutrophils
20%
Possible Mechanisms
20%
Self-limiting
20%
Tert-butyl Hydroperoxide (t-BHP)
20%
Tissue Damage
20%
Immunology and Microbiology
Autacoid
20%
Catalase
40%
Chemotaxis
20%
Erythrocyte Ghost
20%
Hydrogen Peroxide
40%
IC50
20%
Leukotriene A4
20%
Leukotriene B4
100%
Lipid Solubility
20%
Lipoxygenase
60%
Metabolite
20%
Neutrophil
100%
Neutrophil Chemotaxis
40%
Neutrophil Granulocyte
20%
Peroxidation
20%
Tissue Membrane
40%